PUBLICATIONS

2023


Archibald, B.N.*, Zhong, V.*,  Brophy, J.A.N. 

Policy makers, genetic engineers, and an engaged public can work together to create climate-resilient plants

PLOS Biology 21(7):e3002208  [pdf]


Zhong, V.*, Archibald, B.N.*, Brophy, J.A.N. 

Transcriptional and post-transcriptional controls for tuning gene expression in plants

Current Opinion in Plant Biology 71; 102315 [pdf]


Leak, L.B.*, Tamborski, J.*, Commissaris, A., Brophy, J.A.N.

Forging a path toward a more sustainable laboratory

Trends in Biochemical Sciences 48(1): 5-8 [pdf]

2022


Brophy, J.A.N., Magallon, K. J., Duan, L., Zhong, V., Ramachandran, P., Kniazev, K., Dinneny, J.R. 

Synthetic genetic circuits as a means of reprogramming of plant roots 

Science 377(6607): 747-751 [pdf] [supplement]

News Articles & Perspectives: [Science] [Stanford News] [GEN] [Synthetic Biology] [DOE] [Quanta]

Rice, S.L., Lazarus, E., Anderton, E., Birnbaum, K., Brophy, J.A.N., Cole, B., Dickel, D., Erhardt, D., Fahlgren, N., Frank, M., Haswell, E., Huang, S.C., Leiboff, S., Libault, M., Otegui, M.S., Provart, N., Uhrig, R.G., Rhee, S.Y., Plant Cell Atlas Consortium

First Plant Cell Atlas symposium report

Plant Direct 6:e406 [pdf]


Brophy, J.A.N. 

Toward synthetic plant development

Plant Physiology 188(2): 738-748 [pdf]

2021

Becker, M.H., Brophy, J.A.N., Barrett, K., Bronikowski, E., Evans, M., Glassey, E., Klocke, B., Lassiter, E., Meyer, A.J., Kaganer, A.E., Muletz-Wolz, C.R., Fleischer, R.C., Voigt, C.A., Gratwicke, B.

Genetically modifying skin microbe to produce violacein and augmenting microbiome did not defend Panamanian golden frogs from disease

ISME Communications 1: 57 [pdf] [supplement]


Jha, S.G., Borowsky, A.T., Cole, B.J., Fahlgren, N., Farmer, A., Huang, C., Karia, P., Libault, M., Provart, N.J., Rice, S.L., Saura-Sanchez, M., Agarwal, P., Ahkami, A.H., Anderton, C.R., Briggs, S.P., Brophy, J.A.N., Denolf, P., Di Costanzo, L.F., Exposito-Alonso, M., Giacomello, S., Gomez-Cano, F., Kaufmann, K., Ko, D.K., Kumar, S., Malkovskivy, A.V., Nakayama, N., Obata, T., Otegui, M.S., Palfalvi, G., Quezada-Rodriguez, E.H., Singh, R., Uhrig, R.G., Waese, J., Van Wijk, K., Wright, R.C., Ehrhardt, D.W., Birnbaum, K.D., Rhee, S.Y., Plant Cell Atlas Consortium 

Science Forum: Vision, challenges and opportunities for a Plant Cell Atlas

eLife e66877 [pdf]

Cuevas-Velazquez, C.L., Vellosillo, T., Guadalupe, K., Schmidt, H.B., Yu, F., Moses, D., Brophy, J.A.N., Cosio-Acosta, D., Das, A., Wang, L., Jones, A.M., Covarrubias, A.A., Sukenik, S., Dinneny, J.R.

Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells

Nature Communications 12: 5438 [pdf] [supplement]

2018

Brophy, J.A.N., Triassi, A.J., Adams, B.L., Renberg, R.L., Stratis-Cullum, D.N., Grossman, A.D., & Voigt, C.A.

Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria

Nature Microbiology 3(9) 1043-1053 [pdf] [supplement]

Brophy, J.A.N.*, LaRue T.*, & Dinneny, J.R.

Understanding and engineering plant form

Seminars in Cell & Developmental Biology 79, 68-77 [pdf]

2016

Brophy, J.A.N. & Voigt, C.A.

Antisense transcription as a tool to tune gene expression

Molecular Systems Biology 12(1) 854 [pdf] [supplement]

2014

Brophy, J.A.N. & Voigt, C.A.

Principles of genetic circuit design

Nature Methods 11(5) 508-520 [pdf]

2013

Chen, Y-J., Liu, P., Nielsen, A.A.K., Brophy, J.A.N., Clancy, K., Peterson, T., & Voigt, C.A.

Characterization of 582 natural and synthetic terminators and quantification of their design constraints

Nature Methods 10(7) 659-664 [pdf] [supplement]


Leguia, M., Brophy, J.A.N., Densmore, D., Asante, A., Anderson, J.C. 

2ab assembly: a methodology for automatable, high-throughput assembly of standard biological parts

Journal of Biological Engineering 7(1): 1-16 [pdf] 

2011

Leguia, M., Brophy, J.A.N., Densmore, D., & Anderson, J.C.

Automated assembly of standard biological parts

Methods in Enzymology 498, 363-397 [pdf]

2010 

Fu, D., Brophy, J.A.N., Chan, C.T.Y., Atmore, K.A., Begley, U., Paules, R.S., Dedon, P.C., Begley, T.J., & Samson, L.D.

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival 

Molecular and Cellular Biology 30(10), 2449-2459 [pdf]