Synthetic genetic circuits in plants
Synthetic genetic circuits are powerful tools for reprogramming the behavior of living organisms. We are developing synthetic genetic circuits to control gene expression in plants. We are leveraging these circuits to modify the spatiotemporal patterns of gene expression in the model plant Arabidopsis thaliana. The resulting synthetic circuits are then applied to change the plant's growth and behavior.
Controlling form to probe function
Structural features of a plant contribute to its ability to survive in challenging environments. For example, the size and shape of a plant’s root system influences its ability to reach essential nutrients in the soil or to acquire water during drought. Yet, our understanding of relationships between form and function remain limited. We are using synthetic gene circuits to modify the size and shape of plants and testing the modified plants for improved environmental stress tolerance. A better understanding of the plant features that are important for environmental stress tolerance would enable targeted breeding and biotechnological interventions that strengthen our agricultural systems.
Engineered soil bacteria
Plants do not grow in isolation. Much like human microbiota, the bacteria that live in and around plants affect their health. We are developing tools that enable the engineering of undomesticated soil bacteria and are applying them to create designer probiotics that enhance plant growth in challenging environments.
Synthetic Biology Young Speaker Series (SynBYSS) - November 2022
JGI 25th Anniversary - August 2022
UC Berkeley Plant Genome Engineering Symposium - August 2022
Plant Physiology Webinar - February 2022
BioBuilder Career Conversation - January 2022
Synbio Oxford Seminar - April 2021
Bristol BioDesign Institute - March 2021